Clinical interpretation of antineutrophil cytoplasmic antibodies: parvovirus B19 infection as a pitfall
نویسندگان
چکیده
منابع مشابه
Clinical interpretation of antineutrophil cytoplasmic antibodies: parvovirus B19 infection as a pitfall.
BACKGROUND While antibodies directed against proteinase 3 (PR3-ANCA) and myeloperoxidase (MPO-ANCA) have a high specificity for the diagnosis of systemic vasculitis, they may also be found as an epiphenomenon of acute viral infection. OBJECTIVE To investigate whether positive ANCA test results may be a common feature of acute parvovirus B19 infection. METHODS Sera were analysed from 1242 pa...
متن کاملAntineutrophil cytoplasmic antibodies: appropriate use and interpretation.
It was with much interest that we read the letter of Novikov et al on testing for antineutrophil cytoplasmic antibodies (ANCAs) in patients with ANCA-associated vasculitides (AAV) and other diseases. In their letter, the authors (1) share their experience with direct testing for proteinase-3 (PR3) ANCA and myeloperoxidase (MPO) ANCA and (2) raise some important issues regarding interpretation o...
متن کاملClinical presentations of parvovirus B19 infection.
Although most persons with parvovirus B19 infection are asymptomatic or have mild, nonspecific, cold-like symptoms, several clinical conditions have been linked to the virus. Parvovirus B19 usually infects children and causes the classic "slapped-cheek" rash of erythema infectiosum (fifth disease). The virus is highly infectious and spreads mainly through respiratory droplets. By the time the r...
متن کاملAntineutrophil cytoplasmic antibodies.
Antineutrophil cytoplasmic antibodies (ANCA) are predominantly IgG autoantibodies directed against constituents of primary granules of neutrophils and monocytes lysosomes. Although several antigenic targets have been identified, those ANCA directed to proteinase 3 or myeloperoxidase are clinically relevant, whereas the importance of other ANCA remains unknown. Both are strongly associated with ...
متن کاملSeroprevalence of Parvovirus B19 Antibodies in Young Women, Sanandaj, Iran
Background and Aims: Human parvovirus B19 may transmit to the fetus via the placenta during pregnancy and cause serious complications such as severe fetal anemia, non-immune hydrops fetalis, and even intrauterine fetal death. The aim of this study was to determine the seroprevalence of parvovirus B19 antibodies among young women, Sanandaj, Iran. Materials and Methods: Ninety young women (15-40 ...
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ژورنال
عنوان ژورنال: Annals of the Rheumatic Diseases
سال: 2005
ISSN: 0003-4967
DOI: 10.1136/ard.2004.024877